Impact Highlights

AS WE EMBARK ON A NEW DECADE, THE FOUNDATION FOR THE NATIONAL INSTITUTES OF HEALTH (FNIH) IS PROUD TO CONTINUE SUPPORTING THE FIELD OF BIOMEDICAL RESEARCH. PRESENTED HERE ARE A FEW SIGNIFICANT MILESTONES FROM THE PAST DECADE RESULTING IN MEANINGFUL IMPACT IN HEALTH WORLDWIDE.

Created the infrastructure for unparalleled public-private partnerships to accelerate development of new treatments for chronic diseases like Alzheimer’s disease, type 2 diabetes, rheumatoid arthritis, lupus and Parkinson’s disease, by sharing data publicly to advance the science and establish a model for progress.

Qualified the first clinical safety biomarker ever in the history of the U.S. Food and Drug Administration (FDA), leading to improved detection of drug-induced acute kidney injury in clinical trials.

Developed the first-ever evidence-based criteria to diagnose sarcopenia, which will promote the generation of better therapies to treat this condition.

Revealed that exposures to pathogens in children in low-resource settings leads to significant shortfalls in child development — even in the absence of symptoms of any disease — through a paradigm-shifting study.

Pioneered the use of a master protocol for clinical trials in oncology, leading to rapid acceleration of cancer drug testing, extending treatment access to hundreds of cancer patients and paving the way for master protocol use in other disease areas.

Dear Friends,

It has been said that science is a verb: a dynamic process of discovery, innovation and translation.

Put in action, science can solve some of the greatest health challenges facing the world today. Research brings us one step closer to doing just that. The exploration taking place now in research laboratories supported by the National Institutes of Health (NIH) and at the NIH has enabled a more profound scientific understanding of disease than ever before. These new insights lead to novel methods and techniques that facilitate breakthroughs in the ways we diagnose, treat and prevent disease. Such groundbreaking approaches, in turn, make possible practical solutions for health challenges faced by people across the globe.

In these pages, you will see examples of biomedical research moving the needle forward. In 2019, the FNIH launched initiatives that anticipate patients’ response to cancer treatment, ease the burden of diagnosis of a common, deadly liver disease and improve the tuberculosis vaccine — to name just a few. These stories illustrate the unique and crucial role of the FNIH: building and managing cross-sector alliances, convening key stakeholders to tackle complex challenges, investing in the future of scientific leadership, and sharing the results of our collaborations to advance knowledge among the research community.

There is no better example of the importance of our work than our support of the NIH in its urgent and heroic efforts to combat COVID-19 through clinical trials for vaccines and treatments. It has never been clearer that public-private partnerships are critical to solving humanity’s most pressing public health challenges. Collaborations with partners from industry, government, not-for-profit organizations, foundations and individual donors leverage generosity, dedication and expertise to move toward the types of health care solutions that will make a huge difference in all of our lives.

Above all, we wish to highlight our gratitude for your partnership and support in carrying out the mission of the FNIH. Just as research brings us one step closer, research brings us together around the shared desire to achieve our grandest, most transformative goals for human health.

Steven M. Paul, M.D.
Chairman
Maria C. Freire, Ph.D.
President and Executive Director

About Us

The Foundation for the National Institutes of Health (FNIH) forges powerful alliances that advance breakthrough biomedical discoveries and improve the quality of people’s lives. As a 501(c)(3) charity chartered by Congress, the FNIH creates and manages these partnerships with public and private institutions in support of the mission of the National Institutes of Health (NIH), the world’s premier medical research agency. Convening otherwise diverse or competitive research efforts around a common mission, the FNIH brings dynamism, energy and urgency to finding treatments and cures for patients.